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研究業績

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合田研究室は幅広い領域(科学、産業、医療)で影響力のある革新的技術の開発及び発見を行ってきました。以下は合田研究室によって最近発表された代表的な論文です。研究業績の全リストはこちらです。

インテリジェント画像活性細胞選抜法

N. Nitta, T. Sugimura, A. Isozaki, H. Mikami, K. Hiraki, S. Sakuma, T. Iino, F. Arai, T. Endo, Y. Fujiwaki, H. Fukuzawa, M. Hase, T. Hayakawa, K. Hiramatsu, Y. Hoshino, M. Inaba, T. Ito, H. Karakawa, .., T. Yamano, A. Yasumoto, Y. Yatomi, M. Yazawa, D. Di Carlo, Y. Hosokawa, S. Uemura, Y. Ozeki, and K. Goda, "Intelligent image-activated cell sorting," Cell 175, 266 (2018)

金属フリーの表面増強ラマン分光法

N. Chen, T. Xiao, Z. Luo, Y. Kitahama, K. Hiramatsu, N. Kishimoto, T. Itoh, Z. Cheng, and K. Goda, "Porous carbon nanowire array for surface-enhanced Raman spectroscopy," Nature Communications 11, 4772 (2020)

ラマン画像活性細胞選抜法

N. Nitta, T. Iino, A. Isozaki, M. Yamagishi, Y. Kitahama, S. Sakuma, Y. Suzuki, H. Tezuka, M. Oikawa, F. Arai, T. Asai, D. Deng, H. Fukuzawa, M. Hase, T. Hasunuma, T. Hayakawa, .., D. Di Carlo, Y. Hosokawa, S. Uemura, T. Sugimura, Y. Ozeki, and K. Goda, "Raman image-activated cell sorting," Nature Communications 11, 3452 (2020)

細胞培養用の液滴カプセルの超高速分取法

A. Isozaki, Y. Nakagawa, M. H. Loo, Y. Shibata, .., K. Suzuki, S. Ohnuki, Y. Ohya, Y. Kato, T. Hasunuma, S. Matsusaka, M. Yamagishi, M. Yazawa, S. Uemura, K. Nagasawa, H. Watarai, D. Di Carlo, and K. Goda, "Sequentially addressable dielectrophoretic array for high-throughput sorting of large-volume biological compartments", Science Advances 6, eaba6712 (2020)

疑似固定蛍光イメージング

H. Mikami, M. Kawaguchi, C.-J. Huang, H. Matsumura, T. Sugimura, K. Huang, C. Lei, S. Ueno, T. Miura, T. Ito, K. Nagasawa, T. Maeno, H. Watarai, M. Yamagishi, S. Uemura, S. Ohnuki, Y. Ohya, H. Kurokawa, S. Matsusaka, C.-W. Sun, Y. Ozeki, and K. Goda, "Virtual-freezing fluorescence imaging flow cytometry", Nature Communications 11, 1162 (2020)

血小板凝集塊の分類法の発見

Y. Zhou, A. Yasumoto, C. Lei, C.-H. Huang, H. Kobayashi, Y. Wu, S. Yan, C.-W. Sun, Y. Yatomi, and K. Goda, "Intelligent classification of platelet aggregates by agonist type", eLife 9, e52938 (2020)

インテリジェント画像活性細胞選抜法の実践ガイド

A. Isozaki, H. Mikami, K. Hiramatsu, S. Sakuma, Y. Kasai, T. Iino, T. Yamano, A. Yasumoto, Y. Oguchi, .., M. Yamada, S. Matsusaka, T. Hayakawa, H. Fukuzawa, Y. Yatomi, F. Arai, D. Di Carlo, A. Nakagawa, Y. Hoshino, Y. Hosokawa, S. Uemura, T. Sugimura, Y. Ozeki, N. Nitta, and K. Goda, "A practical guide to intelligent image-activated cell sorting," Nature Protocols 14, 2370 (2019)

無標識指紋領域フローサイトメトリー

K. Hiramatsu, T. Ideguchi, Y. Yonamine, S. Lee, Y. Luo, K. Hashimoto, T. Ito, M. Hase, J.-W. Park, Y. Kasai, S. Sakuma, T. Hayakawa, F. Arai, Y. Hoshino, and K. Goda, "High-throughput label-free molecular fingerprinting flow cytometry," Science Advances 4, eaau0241 (2019)

無標識分子イメージングフローサイトメトリー

Y. Suzuki, K. Kobayashi, Y. Wakisaka, .., T. Sugimura, N. Nitta, K. Goda, and Y. Ozeki, "Label-free chemical imaging flow cytometry by high-speed multicolor stimulated Raman scattering," PNAS 116, 15842 (2019)

高速イメージングフローサイトメトリー

C. Lei, H. Kobayashi, Y. Wu, A. Isozaki, A. Yasumoto, H. Mikami, T. Ito, N. Nitta, T. Sugimura, M. Yamada, Y. Yatomi, D. Di Carlo, Y. Ozeki, and K. Goda, "High-throughput imaging flow cytometry by optofluidic time-stretch microscopy," Nature Protocols 13, 1603 (2018)

二種類のプラズモンの相互作用

C. V. Hoang, K. Hayashi, Y. Ito, N. Gorai, G. Allison, X. Shi, Q. Sun, Z. Cheng, K. Ueno, K. Goda, and H. Misawa, "Interplay of hot electrons from localized and propagating plasmons," Nature Communications 8, 771 (2017)

ユーグレナの個性を測る世界最高速分光イメージング法

Y. Wakisaka, Y. Suzuki, O. Iwata, A. Nakashima, T. Ito, M. Hirose, R. Domon, M. Sugawara, N. Tsumura, H. Watarai, T. Shimobaba, K. Suzuki, K. Goda, and Y. Ozeki, "Probing the metabolic heterogeneity of live Euglena gracilis with stimulated Raman scattering microscopy," Nature Microbiology 1, 16124 (2016)

世界最高速のバースト撮像法

K. Nakagawa, A. Iwasaki, Y. Oishi, R. Horisaki, A. Tsukamoto, A. Nakamura, K. Hirosawa, H. Liao, T. Ushida, K. Goda, F. Kannari, and I. Sakuma, "Sequentially timed all-optical mapping photography (STAMP)," Nature Photonics 8, 695 (2014)

世界最高速のシングルショット分光法

K. Goda and B. Jalali, "Dispersive Fourier transformation for fast continuous single-shot measurements," Nature Photonics 7, 102 (2013)

世界最高速の連続撮像法

K. Goda, K. K. Tsia, and B. Jalali, "Serial time-encoded amplified imaging for real-time observation of fast dynamic phenomena," Nature 458, 1145 (2009)

世界最高速のイメージ・サイトメーター

K. Goda, A. Ayazi, D. R. Gossett, J. Sadasivam, C. K. Lonappan, E. Sollier, A. M. Fard, S. C. Hur, J. Adam, C. Murray, C. Wang, N. Brackbill, D. Di Carlo, and B. Jalali, "High-throughput single-microparticle imaging flow analyzer," PNAS 109, 11630 (2012)

量子強化した重力波検出器

K. Goda, O. Miyakawa, E. E> Mikhailov, S. Saraf, R. Adhikari, K. McKenzie, R. Ward, S. Vass, A. J. Weinstein, and N. Mavalvala, "A quantum-enhanced prototype gravitational-wave detector," Nature Physics 4, 472 (2008)